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Agaricus blazei Researches

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 64 Ellertsen LK, Hetland G, Johnson E, Grinde B.  
Abstract Effect of a medicinal extract from Agaricus blazei Murill on gene expression in a human monocyte cell line as examined by microarrays and immuno assays.
Int Immunopharmacol. 2006 Feb;6(2):133-43. Epub 2005 Sep 8.
 63 Zhong M, Tai A, Yamamoto I.  
Free Full Text In vitro augmentation of natural killer activity and interferon-gamma production in murine spleen cells with Agaricus blazei fruiting body fractions.
Biosci Biotechnol Biochem. 2005 Dec;69(12):2466-9.
 62 Ebina T.  
Abstract [Antitumor effects of intratumoral injection of Basidiomycetes preparations]
Gan To Kagaku Ryoho. 2005 Oct;32(11):1654-6. Japanese.
 61 Bernardshaw S, Johnson E, Hetland G.  
Abstract An extract of the mushroom Agaricus blazei Murill administered orally protects against systemic Streptococcus pneumoniae infection in mice.
Scand J Immunol. 2005 Oct;62(4):393-8.
 60 Chen L, Shao H.  
Abstract Extract from Agaricus blazei Murill can enhance immune responses elicited by DNA vaccine against foot-and-mouth disease.
Vet Immunol Immunopathol. 2006 Jan 15;109(1-2):177-82. Epub 2005 Oct 6.
59  Bellini MF, Angeli JP, Matuo R, Terezan AP, Ribeiro LR, Mantovani MS.  
Abstract Antigenotoxicity of Agaricus blazei mushroom organic and aqueous extracts in chromosomal aberration and cytokinesis block micronucleus assays in CHO-k1 and HTC cells.
Toxicol In Vitro. 2006 Apr;20(3):355-60. Epub 2005 Sep 22.
 58 Ker YB, Chen KC, Chyau CC, Chen CC, Guo JH, Hsieh CL, Wang HE, Peng CC, Chang CH, Peng RY.  
Abstract Antioxidant capability of polysaccharides fractionated from submerge-cultured Agaricus blazei mycelia.
J Agric Food Chem. 2005 Sep 7;53(18):7052-8.
 57 Kim GY, Lee MY, Lee HJ, Moon DO, Lee CM, Jin CY, Choi YH, Jeong YK, Chung KT, Lee JY, Choi IH, Park YM.  
Abstract Effect of water-soluble proteoglycan isolated from Agaricus blazei on the maturation of murine bone marrow-derived dendritic cells.
Int Immunopharmacol. 2005 Sep;5(10):1523-32. Epub 2005 Apr 1.
 56 Yoshimura K, Ueda N, Ichioka K, Matsui Y, Terai A, Arai Y.  
Abstract Use of complementary and alternative medicine by patients with urologic cancer: a prospective study at a single Japanese institution.
Support Care Cancer. 2005 Sep;13(9):685-90. Epub 2005 Jun 10.
 55 Kim YW, Kim KH, Choi HJ, Lee DS.  
Abstract Anti-diabetic activity of beta-glucans and their enzymatically hydrolyzed oligosaccharides from Agaricus blazei.
Biotechnol Lett. 2005 Apr;27(7):483-7.
 54 Kobayashi H, Yoshida R, Kanada Y, Fukuda Y, Yagyu T, Inagaki K, Kondo T, Kurita N, Suzuki M, Kanayama N, Terao T.  
Abstract Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse model.
J Cancer Res Clin Oncol. 2005 Aug;131(8):527-38. Epub 2005 May 10.
 53 Kasai H, He LM, Kawamura M, Yang PT, Deng XW, Munkanta M, Yamashita A, Terunuma H, Hirama M, Horiuchi I, Natori T, Koga T, Amano Y, Yamaguchi N, Ito M.  
Free in PMC IL-12 Production Induced by Agaricus blazei Fraction H (ABH) Involves Toll-like Receptor (TLR).
Evid Based Complement Alternat Med. 2004 Dec;1(3):259-267.
 52 Kuroiwa Y, Nishikawa A, Imazawa T, Kanki K, Kitamura Y, Umemura T, Hirose M.  
Abstract Lack of subchronic toxicity of an aqueous extract of Agaricus blazei Murrill in F344 rats.
Food Chem Toxicol. 2005 Jul;43(7):1047-53.
 51 Machado MP, Filho ER, Terezan AP, Ribeiro LR, Mantovani MS.  
Abstract Cytotoxicity, genotoxicity and antimutagenicity of hexane extracts of Agaricus blazei determined in vitro by the comet assay and CHO/HGPRT gene mutation assay.
Toxicol In Vitro. 2005 Jun;19(4):533-9.
 50 Kimura Y.  
Abstract New anticancer agents: in vitro and in vivo evaluation of the antitumor and antimetastatic actions of various compounds isolated from medicinal plants.
In Vivo. 2005 Jan-Feb;19(1):37-60. Review.
 49 Kawamura M, Kasai H, He L, Deng X, Yamashita A, Terunuma H, Horiuchi I, Tanabe F, Ito M.  
Abstract Antithetical effects of hemicellulase-treated Agaricus blazei on the maturation of murine bone-marrow-derived dendritic cells.
Immunology. 2005 Mar;114(3):397-409.
 48 Kubo N, Myojin Y, Shimamoto F, Kashimoto N, Kyo E, Kamiya K, Watanabe H.  
Abstract Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice: Increased small intestinal crypt survival and prolongation of average time to animal death.
Int J Mol Med. 2005 Mar;15(3):401-6.
 47 Ullrich R, Huong le M, Dung NL, Hofrichter M.  
Abstract Laccase from the medicinal mushroom Agaricus blazei: production, purification and characterization.
Appl Microbiol Biotechnol. 2005 May;67(3):357-63. Epub 2005 Jan 13
 46 Kimura Y, Kido T, Takaku T, Sumiyoshi M, Baba K.  
Abstract Isolation of an anti-angiogenic substance from Agaricus blazei Murill: its antitumor and antimetastatic actions.
Cancer Sci. 2004 Sep;95(9):758-64.
 45 Ahn WS, Kim DJ, Chae GT, Lee JM, Bae SM, Sin JI, Kim YW, Namkoong SE, Lee IP.  
Abstract Natural killer cell activity and quality of life were improved by consumption of a mushroom extract, Agaricus blazei Murill Kyowa, in gynecological cancer patients undergoing chemotherapy.
Int J Gynecol Cancer. 2004 Jul-Aug;14(4):589-94.
 44 Dos Santos AZ, Candido Neto JM, Granhen Tavares CR, Gomes Da Costa SM.  
Abstract Screening of filamentous fungi for the decolorization of a commercial reactive dye.
J Basic Microbiol. 2004;44(4):288-95.
 43 Kaneno R, Fontanari LM, Santos SA, Di Stasi LC, Rodrigues Filho E, Eira AF.  
Abstract Effects of extracts from Brazilian sun-mushroom (Agaricus blazei) on the NK activity and lymphoproliferative responsiveness of Ehrlich tumor-bearing mice.
Food Chem Toxicol. 2004 Jun;42(6):909-16.
 42 Shu CH, Wen BJ, Lin KJ.  
Abstract Monitoring the polysaccharide quality of Agaricus blazei in submerged culture by examining molecular weight distribution and TNF-alpha release capability of macrophage cell line RAW 264.7.
Biotechnol Lett. 2004 Feb;26(4):2061-4.
 41 Guterrez ZR, Mantovani MS, Eira AF, Ribeiro LR, Jordao BQ.  
Abstract Variation of the antimutagenicity effects of water extracts of Agaricus blazei Murrill in vitro.
Toxicol In Vitro. 2004 Jun;18(3):301-9.
 40 Chen L, Shao HJ, Su YB.  
Abstract Coimmunization of Agaricus blazei Murill extract with hepatitis B virus core protein through DNA vaccine enhances cellular and humoral immune responses.
Int Immunopharmacol. 2004 Mar;4(3):403-9.
 39 Xing Z, Guo Q, Feng Z, Guo L, Liu Y.  
Abstract Analysis on the volatile flavor compounds in Agaricus blazei by GC-MS]. Zhong Yao Cai. 2003 Nov;26(11):789-91. Chinese.
PMID: 14989059 [PubMed - indexed for MEDLINE]
 38 Shu CH, Wen BJ, Lin KJ.  
Abstract Monitoring the polysaccharide quality of Agaricus blazei in submerged culture by examining molecular weight distribution and TNF-alpha release capability of macrophage cell line RAW 264.7.
Biotechnol Lett. 2003 Dec;25(24):2061-4.
 37 Izawa S, Inoue Y.  
Abstract A screening system for antioxidants using thioredoxin-deficient yeast: discovery of thermostable antioxidant activity from Agaricus blazei Murill.
Appl Microbiol Biotechnol. 2003 Oct 31 [Epub ahead of print]
PMID: 14593506 [PubMed - as supplied by publisher]
 36 Pinheiro F, Faria RR, de Camargo JL, Spinardi-Barbisan AL, da Eira AF, Barbisan LF.  
Abstract Chemoprevention of preneoplastic liver foci development by dietary mushroom Agaricus blazei Murrill in the rat.
Food Chem Toxicol. 2003 Nov;41(11):1543-50.
PMID: 12963007 [PubMed - in process]
35 Shu CH, Wen BJ.  
Abstract Enhanced shear protection and increased production of an anti-tumor polysaccharide by Agaricus blazei in xanthan-supplemented cultures.
Biotechnol Lett. 2003 Jun;25(11):873-6.
PMID: 12889797 [PubMed - indexed for MEDLINE]
 34 Luiz RC, Jordao BQ, da Eira AF, Ribeiro LR, Mantovani MS.  
Abstract Mechanism of anticlastogenicity of Agaricus blazei Murill mushroom organic extracts in wild type CHO (K(1)) and repair deficient (xrs5) cells by chromosome aberration and sister chromatid exchange assays.
Mutat Res. 2003 Jul 25;528(1-2):75-9.
PMID: 12873725 [PubMed - indexed for MEDLINE]
 33 Bellini MF, Giacomini NL, Eira AF, Ribeiro LR, Mantovani MS.  
Abstract Anticlastogenic effect of aqueous extracts of Agaricus blazei on CHO-k1 cells, studying different developmental phases of the mushroom.
Toxicol In Vitro. 2003 Aug;17(4):465-9.
PMID: 12849730 [PubMed - in process]
 32 Barbisan LF, Spinardi-Barbisan AL, Moreira EL, Salvadori DM, Ribeiro LR, da Eira AF, de Camargo JL.  
Free Full Text Agaricus blazei (Himematsutake) does not alter the development of rat diethylnitrosamine-initiated hepatic preneoplastic foci.
Cancer Sci. 2003 Feb;94(2):188-92.
PMID: 12708495 [PubMed - indexed for MEDLINE]
 31 Martins de Oliveira J, Jordao BQ, Ribeiro LR, Ferreira da Eira A, Mantovani MS.  
Abstract Anti-genotoxic effect of aqueous extracts of sun mushroom (Agaricus blazei Murill lineage 99/26) in mammalian cells in vitro.
Food Chem Toxicol. 2002 Dec;40(12):1775-80.
PMID: 12419691 [PubMed - indexed for MEDLINE]
 30 Barbisan LF, Miyamoto M, Scolastici C, Salvadori DM, Ribeiro LR, Eira AF, de Camargo JL.  
Abstract Influence of aqueous extract of Agaricus blazei on rat liver toxicity induced by different doses of diethylnitrosamine.
J Ethnopharmacol. 2002 Nov;83(1-2):25-32.
PMID: 12413704 [PubMed - indexed for MEDLINE]
 29 Hirotani M, Sai K, Nagai R, Hirotani S, Takayanagi H, Yoshikawa T.  
Abstract Blazeispirane and protoblazeispirane derivatives from the cultured mycelia of the fungus Agaricus blazei.
Phytochemistry. 2002 Nov;61(5):589-95.
PMID: 12409027 [PubMed - indexed for MEDLINE]
 28 Shimizu S, Kitada H, Yokota H, Yamakawa J, Murayama T, Sugiyama K, Izumi H, Yamaguchi N.  
Abstract Activation of the alternative complement pathway by Agaricus blazei Murill.
Phytomedicine. 2002 Sep;9(6):536-45.
PMID: 12403163 [PubMed - indexed for MEDLINE]
 27 Nakajima A, Ishida T, Koga M, Takeuchi T, Mazda O, Takeuchi M.  
Abstract Effect of hot water extract from Agaricus blazei Murill on antibody-producing cells in mice.
Int Immunopharmacol. 2002 Jul;2(8):1205-11.
PMID: 12349957 [PubMed - indexed for MEDLINE]
 26 Kuo YC, Huang YL, Chen CC, Lin YS, Chuang KA, Tsai WJ.  
Abstract Cell cycle progression and cytokine gene expression of human peripheral blood mononuclear cells modulated by Agaricus blazei.
J Lab Clin Med. 2002 Sep;140(3):176-87.
PMID: 12271275 [PubMed - indexed for MEDLINE]
 25 Hashimoto T, Nonaka Y, Minato K, Kawakami S, Mizuno M, Fukuda I, Kanazawa K, Ashida H.  
Free Full Text Suppressive effect of polysaccharides from the edible and medicinal mushrooms, Lentinus edodes and Agaricus blazei, on the expression of cytochrome P450s in mice.
Biosci Biotechnol Biochem. 2002 Jul;66(7):1610-4.
PMID: 12224654 [PubMed - indexed for MEDLINE]
 24 Dong Q, Yao J, Yang XT, Fang JN.  
Abstract Structural characterization of a water-soluble beta-D-glucan from fruiting bodies of Agaricus blazei Murr.
Carbohydr Res. 2002 Sep 3;337(15):1417-21.
PMID: 12204626 [PubMed - indexed for MEDLINE]
 23 Talorete TP, Isoda H, Maekawa T.  
Abstract Agaricus blazei (class Basidiomycotina) aqueous extract enhances the expression of c-Jun protein in MCF7 cells.
J Agric Food Chem. 2002 Aug 28;50(18):5162-6.
PMID: 12188624 [PubMed - indexed for MEDLINE]
 22 Oshiman K, Fujimiya Y, Ebina T, Suzuki I, Noji M.  
Abstract Orally administered beta-1,6-D-polyglucose extracted from Agaricus blazei results in tumor regression in tumor-bearing mice.
Planta Med. 2002 Jul;68(7):610-4.
PMID: 12142994 [PubMed - indexed for MEDLINE]
 21 Hirotani M, Sai K, Hirotani S, Yoshikawa T.  
Abstract Blazeispirols B, C, E and F, des-A-ergostane-type compounds, from the cultured mycelia of the fungus Agaricus blazei.
Phytochemistry. 2002 Mar;59(5):571-7.
PMID: 11853754 [PubMed - indexed for MEDLINE]
 20 Levery SB, Toledo MS, Straus AH, Takahashi HK.  
Abstract Comparative analysis of glycosylinositol phosphorylceramides from fungi by electrospray tandem mass spectrometry with low-energy collision-induced dissociation of Li(+) adduct ions.
Rapid Commun Mass Spectrom. 2001;15(23):2240-58.
PMID: 11746891 [PubMed - indexed for MEDLINE]
 19 Nagata J, Higashiuesato Y, Maeda G, Chinen I, Saito M, Iwabuchi K, Onoe K.  
Abstract Effects of water-soluble hemicellulose from soybean hull on serum antibody levels and activation of macrophages in rats.
J Agric Food Chem. 2001 Oct;49(10):4965-70.
PMID: 11600052 [PubMed - indexed for MEDLINE]
 18 Delmanto RD, de Lima PL, Sugui MM, da Eira AF, Salvadori DM, Speit G, Ribeiro LR.  
Abstract Antimutagenic effect of Agaricus blazei Murrill mushroom on the genotoxicity induced by cyclophosphamide.
Mutat Res. 2001 Sep 20;496(1-2):15-21.
PMID: 11551476 [PubMed - indexed for MEDLINE]
 17 Menoli RC, Mantovani MS, Ribeiro LR, Speit G, Jordao BQ.  
Abstract Antimutagenic effects of the mushroom Agaricus blazei Murrill extracts on V79 cells.
Mutat Res. 2001 Sep 20;496(1-2):5-13.
PMID: 11551475 [PubMed - indexed for MEDLINE]
 16 Sorimachi K, Ikehara Y, Maezato G, Okubo A, Yamazaki S, Akimoto K, Niwa A.  
Free Full Text Inhibition by Agaricus blazei Murill fractions of cytopathic effect induced by western equine encephalitis (WEE) virus on VERO cells in vitro.
Biosci Biotechnol Biochem. 2001 Jul;65(7):1645-7.
PMID: 11515550 [PubMed - indexed for MEDLINE]
15 Okamura T, Ogata T, Minamimoto N, Takeno T, Noda H, Fukuda S, Ohsugi M.  
Free Full Text Characteristics of wine produced by mushroom fermentation.
Biosci Biotechnol Biochem. 2001 Jul;65(7):1596-600.
PMID: 11515544 [PubMed - indexed for MEDLINE]
 14 Sorimachi K, Akimoto K, Ikehara Y, Inafuku K, Okubo A, Yamazaki S.  
Free Full Text Secretion of TNF-alpha, IL-8 and nitric oxide by macrophages activated with Agaricus blazei Murill fractions in vitro.
Cell Struct Funct. 2001 Apr;26(2):103-8.
PMID: 11482452 [PubMed - indexed for MEDLINE]
 13 Ohno N, Furukawa M, Miura NN, Adachi Y, Motoi M, Yadomae T.  
Free Full Text Antitumor beta glucan from the cultured fruit body of Agaricus blazei.
Biol Pharm Bull. 2001 Jul;24(7):820-8.
PMID: 11456124 [PubMed - indexed for MEDLINE]
 12 Takaku T, Kimura Y, Okuda H.  
Free Full Text Isolation of an antitumor compound from Agaricus blazei Murill and its mechanism of action.
J Nutr. 2001 May;131(5):1409-13.
PMID: 11340091 [PubMed - indexed for MEDLINE]
 11 Mizuno M, Minato K, Ito H, Kawade M, Terai H, Tsuchida H.  
Abstract Anti-tumor polysaccharide from the mycelium of liquid-cultured Agaricus blazei mill.
Biochem Mol Biol Int. 1999 Apr;47(4):707-14.
PMID: 10319424 [PubMed - indexed for MEDLINE]
 10 Fujimiya Y, Suzuki Y, Katakura R, Ebina T.  
Abstract Tumor-specific cytocidal and immunopotentiating effects of relatively low molecular weight products derived from the basidiomycete, Agaricus blazei Murill.
Anticancer Res. 1999 Jan-Feb;19(1A):113-8.
PMID: 10226531 [PubMed - indexed for MEDLINE]
9 Ebina T, Fujimiya Y.  
Abstract Antitumor effect of a peptide-glucan preparation extracted from Agaricus blazei in a double-grafted tumor system in mice.
Biotherapy. 1998;11(4):259-65.
PMID: 9950102 [PubMed - indexed for MEDLINE]
 8 Fujimiya Y, Suzuki Y, Oshiman K, Kobori H, Moriguchi K, Nakashima H, Matumoto Y, Takahara S, Ebina T, Katakura R.  
Abstract Selective tumoricidal effect of soluble proteoglucan extracted from the basidiomycete, Agaricus blazei Murill, mediated via natural killer cell activation and apoptosis.
Cancer Immunol Immunother. 1998 May;46(3):147-59.
PMID: 9625538 [PubMed - indexed for MEDLINE]
 7 Mizuno M, Morimoto M, Minato K, Tsuchida H.  
Abstract Polysaccharides from Agaricus blazei stimulate lymphocyte T-cell subsets in mice.
Biosci Biotechnol Biochem. 1998 Mar;62(3):434-7.
PMID: 9571772 [PubMed - indexed for MEDLINE]
 6 Higaki M, Eguchi F, Watanabe Y.  
Abstract [A stable culturing method and pharmacological effects of the Agaricus blazei]
Nippon Yakurigaku Zasshi. 1997 Oct;110 Suppl 1:98P-103P. Japanese.
PMID: 9503414 [PubMed - indexed for MEDLINE]
 5 Ito H, Shimura K, Itoh H, Kawade M.  
Abstract Antitumor effects of a new polysaccharide-protein complex (ATOM) prepared from Agaricus blazei (Iwade strain 101) "Himematsutake" and its mechanisms in tumor-bearing mice.
Anticancer Res. 1997 Jan-Feb;17(1A):277-84.
PMID: 9066665 [PubMed - indexed for MEDLINE]
 4 Itoh H, Ito H, Amano H, Noda H.  
Abstract Inhibitory action of a (1-->6)-beta-D-glucan-protein complex (F III-2-b) isolated from Agaricus blazei Murill ("himematsutake") on Meth A fibrosarcoma-bearing mice and its antitumor mechanism.
Jpn J Pharmacol. 1994 Oct;66(2):265-71.
PMID: 7869611 [PubMed - indexed for MEDLINE]
 3 Osaki Y, Kato T, Yamamoto K, Okubo J, Miyazaki T.  
Abstract [Antimutagenic and bactericidal substances in the fruit body of a Basidiomycete Agaricus blazei, Jun-17]
Yakugaku Zasshi. 1994 May;114(5):342-50. Japanese.
PMID: 8014843 [PubMed - indexed for MEDLINE]
 2 Kawagishi H, Inagaki R, Kanao T, Mizuno T, Shimura K, Ito H, Hagiwara T, Nakamura T.  
Abstract Fractionation and antitumor activity of the water-insoluble residue of Agaricus blazei fruiting bodies.
Carbohydr Res. 1989 Mar 15;186(2):267-73.
PMID: 2736561 [PubMed - indexed for MEDLINE]
 1 Kawagishi H, Nomura A, Yumen T, Mizuno T, Hagiwara T, Nakamura T.  
No abstract Isolation and properties of a lectin from the fruiting bodies of Agaricus blazei.
Carbohydr Res. 1988 Nov 15;183(1):150-4. No abstract available.
PMID: 3233595 [PubMed - indexed for MEDLINE]

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